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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIP4K2B
All Species:
17.58
Human Site:
Y117
Identified Species:
35.15
UniProt:
P78356
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P78356
NP_003550.1
416
47378
Y117
F
G
I
D
D
Q
D
Y
Q
N
S
V
T
R
S
Chimpanzee
Pan troglodytes
XP_001172818
377
42820
D113
L
R
E
R
F
G
I
D
D
Q
D
Y
Q
N
S
Rhesus Macaque
Macaca mulatta
XP_001099389
382
43672
D115
A
R
F
H
T
S
Y
D
K
R
Y
I
I
K
T
Dog
Lupus familis
XP_548154
416
47327
Y117
F
G
I
D
D
Q
D
Y
Q
N
S
V
T
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q80XI4
416
47300
Y117
F
G
I
D
D
Q
D
Y
Q
N
S
V
T
R
S
Rat
Rattus norvegicus
O88377
416
47245
Y117
F
G
I
D
D
Q
D
Y
Q
N
S
V
T
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510625
479
54696
F181
F
G
I
D
D
Q
D
F
Q
N
S
L
T
R
S
Chicken
Gallus gallus
Q5F356
405
46073
F111
F
G
I
D
D
Q
D
F
Q
N
S
L
T
R
S
Frog
Xenopus laevis
Q5PQ01
419
47633
Q123
E
R
F
G
I
D
D
Q
D
F
Q
V
S
L
T
Zebra Danio
Brachydanio rerio
Q6IQE1
416
47361
L115
E
R
F
G
I
E
D
L
D
Y
Q
A
S
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392797
416
47916
Y110
F
G
I
D
D
L
D
Y
K
E
S
M
T
R
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RY89
769
87385
M427
K
L
D
A
A
D
Y
M
M
S
I
C
G
D
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.5
69.4
99.2
N.A.
99
98.3
N.A.
62
77.6
67.7
65.3
N.A.
N.A.
58.6
N.A.
N.A.
Protein Similarity:
100
89.4
80
99.7
N.A.
99.7
99
N.A.
73
88.9
82
80.5
N.A.
N.A.
74
N.A.
N.A.
P-Site Identity:
100
6.6
0
100
N.A.
100
100
N.A.
86.6
86.6
13.3
6.6
N.A.
N.A.
73.3
N.A.
N.A.
P-Site Similarity:
100
6.6
26.6
100
N.A.
100
100
N.A.
100
100
26.6
26.6
N.A.
N.A.
86.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
9
9
0
0
0
0
0
0
9
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
0
9
59
59
17
75
17
25
0
9
0
0
9
9
% D
% Glu:
17
0
9
0
0
9
0
0
0
9
0
0
0
0
0
% E
% Phe:
59
0
25
0
9
0
0
17
0
9
0
0
0
0
0
% F
% Gly:
0
59
0
17
0
9
0
0
0
0
0
0
9
0
0
% G
% His:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
59
0
17
0
9
0
0
0
9
9
9
0
0
% I
% Lys:
9
0
0
0
0
0
0
0
17
0
0
0
0
9
0
% K
% Leu:
9
9
0
0
0
9
0
9
0
0
0
17
0
17
0
% L
% Met:
0
0
0
0
0
0
0
9
9
0
0
9
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
50
0
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
50
0
9
50
9
17
0
9
0
0
% Q
% Arg:
0
34
0
9
0
0
0
0
0
9
0
0
0
59
0
% R
% Ser:
0
0
0
0
0
9
0
0
0
9
59
0
17
0
67
% S
% Thr:
0
0
0
0
9
0
0
0
0
0
0
0
59
0
17
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
42
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
17
42
0
9
9
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _